Synthesis, Spectroscopic Analysis and Antidiabetic Properties of Copper (II) Complex of Mangifera indica Leaf Crude Extract

Many applied conventional drugs in treating diabetes have been reported to possess some drawbacks which necessitate a search for alternative therapies. In order more active antidiabetic agent, this study synthesized and evaluated properties of Mangifera indica crude extract its Cu (II) complex alloxan-induced diabetic albino rats. The leaf metal were characterized using percentage analysis IR spectroscopic data. Experimental animals induced by single intraperitoneal injection Alloxan monohydrate at dose 140 mg/kg body weight with fasting blood glucose level (BGL) > 200 mg/dL considered diabetic. Metformin was used as standard drug. Fasting assess the activity. One-way ANOVA determine statistically significant p< 0.05. found coordinate ion through O donor atom C=O O-H phenol ketone respectively. extracts tested 600mg/kg demonstrated activity without gain than It is concluded that could be potential material development negative-side-effect-free